response treatment 16.3 A 12.8 A 12.4 A 3.3 A 5.4 A 20.0 A 20.5 A 5.6 A 6.6 A 18.0 A 27.0 A 4.4 A 28.9 A 14.6 A 30.8 A 18.6 A 23.6 A 3.0 A 22.1 A 4.1 A 7.8 A 7.2 A 14.6 B 14.1 B 6.3 B 2.8 B 3.9 B 18.2 B 20.6 B 4.9 B 9.8 B 21.0 B 19.0 B 3.6 B 11.8 B 14.1 B 22.6 B 12.2 B 19.1 B 3.0 B 5.3 B 3.7 B 3.9 B 4.0 B 16.6 C 32.7 C 7.2 C 2.5 C 3.8 C 28.3 C 21.3 C 14.1 C 11.5 C 23.4 C 33.0 C 3.6 C 40.8 C 15.0 C 20.7 C 25.1 C 24.0 C 4.1 C 20.5 C 27.7 C 16.4 C 3.1 C 16.4 D 22.0 D 5.1 D 3.3 D 2.9 D 24.6 D 20.3 D 7.8 D 5.1 D 18.7 D 16.0 D 3.3 D 22.5 D 11.8 D 20.5 D 16.0 D 24.0 D 3.4 D 10.4 D 19.4 D 10.3 D 11.1 D